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Lyophilized powder can tolerate longer storage because water has not been added yet

2 The native hormone has a serious pharmaceutical liability: it is prone to aggregation into amyloid fibrils and has a plasma half-life measured in minutes, which is why the first amylin-based drug, pramlintide, had to be injected before every major meal

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A gut lipid messenger links excess dietary fat to dopamine deficiency

16 Exogenous testosterone, even in men with low endogenous testosterone production, suppresses release of hypothalamic and pituitary hormones needed to stimulate testicular function